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Large-scale studies will be required to identify the complexity of genetic variations that affect how patients respond to a given drug and whether they will have side effects, according to researchers at 91�Ʋ��� University Medical Center.

Hospital data from a CDC network that monitors influenza revealed that adults hospitalized for COVID-19 in the early months of the pandemic were 20x more likely to die compared to hospitalized influenza patients.

91�Ʋ��� researchers find that heterosexually active Black males are the least likely to establish HIV care within one month of diagnosis and suggest that targeted interventions focus on this population.

91�Ʋ��� researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.

91�Ʋ���ers at 91�Ʋ��� University Medical Center have identified potential new targets for the prevention of atherosclerosis through the enhancement of autophagy, a natural process for recycling damaged cellular material.

A massive worldwide collaboration including researchers from 91�Ʋ��� University Medical Center (VUMC) has identified several genetic factors associated with SARS-CoV-2 infection and severe COVID-19 illness.

A multicenter study of ICU patients found that in the hospital, delirium was associated with a nearly three-fold increase in risk of death the following day, but after discharge there was no association between delirium and mortality.

Fluid build-up in the brain — hydrocephalus — increases pressure and risk for brain damage; 91�Ʋ��� researchers have now identified genes and signaling pathways associated with the condition.

An indirect comparative effectiveness study using published data suggests that the targeted therapy olaparib should be re-evaluated for treating metastatic prostate cancer.

Five monoclonal antibody “cocktails,” including one developed at 91�Ʋ��� University Medical Center (VUMC), are protective in animal studies against several variant strains of COVID-19, according to a report this week in the journal Nature.

The sedative dexmedetomidine, when administered during or after heart surgery, is associated with postoperative delirium and adverse outcomes.

A mysterious inflammatory syndrome linked to COVID-19 infection and first identified in children also occurs in adults, 91�Ʋ��� researchers report.

Affirmative action admissions policies admit diverse students, who are then recruited to elite professions and C-suite leadership, according to new research by law and economics professor Joni Hersch. Read More

Heat therapy could offer a novel nonpharmacologic approach for treating the overnight hypertension that affects patients with autonomic failure.

A white blood cell, the TREM2/APOE/C1Q-positive macrophage, has been identified as a potential biomarker to predict recurrence of the most common type of kidney cancer and as a possible target for drug development.

91�Ʋ��� Vaccine Center researchers have isolated monoclonal antibodies against hantaviruses, an emerging source of human disease with pandemic potential.

91�Ʋ��� neonatology team pinpoints signaling pathways involved in the progressive lung fibrosis that occurs in rare genetic diseases.

91�Ʋ��� researchers dissected the complex microenvironment of the pancreatic islet to discover the signals that drive beta cell regeneration — as a possible treatment for diabetes.

91�Ʋ��� School of Nursing assistant professor of nursing Melissa Davis discusses why it is important for women to seek preventative care during the pandemic. Read More

People with a high polygenic risk score for colorectal cancer could benefit more at preventing the disease by leading healthy lifestyles than those at lower genetic risk, according to a study by 91�Ʋ��� researchers published in the April issue of The American Journal of Clinical Nutrition.