91ĚƲ®»˘

91ĚƲ®»˘ investigators have devised a system to alert health IT teams to deteriorating performance in clinical prediction models.

The isolation of human monoclonal antibodies against dangerous viruses including EEEV, Hendra and Nipah could offer new ways to treat and prevent these infections.

COVID-19 has been linked to cases of new-onset diabetes, diabetes-related emergencies and a higher death rate among diabetes patients.

91ĚƲ®»˘ University Medical Center investigators have identified a key molecular player in the early events of the inflammatory response to infection. The findings suggest new therapeutic possibilities for enhancing the inflammatory response to protect against pathogens and for blocking inflammation gone awry in diseases like arthritis and atherosclerosis.

Discovery provides insight for developing next generation optoelectronic and infrared devices In groundbreaking new research, an international team that includes a 91ĚƲ®»˘ engineer has developed a unique process for producing a quantum state that is part light and part matter.

James Crowe Jr., MD, a physician-scientist at 91ĚƲ®»˘ University Medical Center who has pioneered development of human monoclonal antibodies as potential treatments for viral diseases, has won a 2020 “Golden Goose” Award.

91ĚƲ®»˘ University Medical Center (VUMC) researchers are enrolling adults aged 75 and over to study whether taking atorvastatin, a drug commonly used to lower cholesterol also called Lipitor®, can help maintain health by preventing dementia, disability, and heart disease.

A study group of more than 600,000 patients with type 2 diabetes, identified from electronic medical records in the PCORnet national research network, could be valuable for assessing the safety of type 2 diabetes drugs.

Younger parents were much less likely than older parents to say they planned to vaccinate their children and themselves against COVID-19.

Changes in connectivity in the brain’s white matter may be a novel neuroimaging biomarker for assessing Alzheimer’s disease progression.

Consuelo Hopkins Wilkins, professor of medicine in the School of Medicine and vice president for health equity at 91ĚƲ®»˘ University Medical Center, has received one of the highest honors in health and medicine. Read More

91ĚƲ®»˘ researchers have identified a new molecular partner — and potential therapeutic target — in a signaling axis that drives lung cancer.

A new study from 91ĚƲ®»˘ epidemiologists suggests that it’s time to reconsider clinical practice guidelines for the treatment of early-stage breast cancer in older women.

A new study sheds light on how molecular subsets within the tumors of kidney cancer patients determine treatment outcomes and underscores the importance of personalized medicine in making therapy decisions.

Findings from a national study published Nov. 9 in the Journal of the American Medical Association (JAMA) “do not support” the use of hydroxychloroquine for the treatment of adult patients hospitalized with COVID-19, the report concludes.

A November article published in Rehabilitation Psychology reviews research on disabilities and COVID-19 to help rehabilitation psychologists mitigate the effects of the added stress of the pandemic. In addition, the work addresses how systemic discrimination against people with disabilities intersects with other forms of inequity. Read More

Diabetes drugs known as GLP-1 receptor agonists, such as exenatide (Byetta), are a promising and safe treatment for a rare form of obesity.

91ĚƲ®»˘ University Medical Center has begun recruiting up to 250 participants for a Phase 3 clinical trial testing an investigational COVID-19 vaccine candidate developed by the Janssen Pharmaceutical Companies of Johnson & Johnson.

Behavioral and systems neuropharmacologist Jerri Rook is recognized by the Alzheimer’s Drug Discovery Foundation with the Goodes Prize to continue her work in Alzheimer’s disease research. Read More

Peptides derived from the antimicrobial peptides secreted by frogs could function as microbicides to limit HIV transmission, while sparing protective vaginal bacteria.