91ÌƲ®»¢

A protein with important functions in astrocytes — star-shaped brain support cells — may alter neuronal excitability and contribute to seizure activity, 91ÌƲ®»¢ researchers report.

91ÌƲ®»¢ researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension.

Understanding the dynamic regulation of cytoskeletal microtubules may suggest new ways to treat disorders ranging from Alzheimer's disease to cancer.

According to a new study, the tiny zebrafish may hold the secret to regenerating damaged retinas in humans.

91ÌƲ®»¢ers at 91ÌƲ®»¢ University Medical Center are partnering with the Dutch biopharmaceutical firm Batavia Biosciences and Nashville-based IDBiologics to bring to the clinic a highly potent Zika virus neutralizing antibody they isolated three years ago.

Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells.

Colorectal cancer researchers from 91ÌƲ®»¢-Ingram Cancer Center (VICC) have been awarded a Specialized Program of 91ÌƲ®»¢ Excellence grant from the National Cancer Institute (NCI).

Gene variants associated with cancer risk appear to contribute to carcinogenesis by regulating target genes that in turn promote the generation of mutations.

91ÌƲ®»¢’s Bruce Carter and colleagues have discovered how genetic changes in the protein PMP22 may contribute to a disease of peripheral nerves.

Combining immunotherapy and radiation therapy may be a powerful treatment approach for castration-resistant prostate cancer.

Breast cancer researchers at 91ÌƲ®»¢-Ingram Cancer Center have secured a fourth round of continuous Specialized Program of 91ÌƲ®»¢ Excellence funding.

91ÌƲ®»¢ers have made a paradigm-shifting discovery that could lead to new treatments, better health and longer life for patients with Type 1 diabetes.

A study led by Anna Vilgelm, MD, PhD, and Ann Richmond, PhD, has identified a possible second-line treatment for melanoma patients.

Investigators are exploring the molecular mechanisms behind the association of chronic inflammation and colon cancer.

Fifteen years after it was launched, REDCap, 91ÌƲ®»¢ University’s research data management tool, has reached 1 million users throughout the world.

Scarcely a year after its national launch, the “All of Us” research program, which aims to accelerate the prevention and treatment of disease, has enrolled more than 230,000 research participants — more than a fifth of its recruitment goal of 1 million people. All

Written by Heidi Hall Alpacas aren’t the typical animals that drivers spot as they wind their way through rural Tennessee, but there’s a happy herd of them outside Waverly, where they eat the finest pellets, walk up and down a scenic hill and potentially save lives. They’re owned by… Read More

91ÌƲ®»¢ investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health.

Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer.

Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases.