91�Ʋ���

An $8.9 million grant from the NIH will establish the 91�Ʋ��� AUD 91�Ʋ��� and Education Center, enhancing 91�Ʋ��� University’s national leadership in neuroscience and addiction research. This initiative aims to foster interdisciplinary collaboration, advance understanding and treatment of alcohol use disorder, and engage the public through education and outreach efforts. Read More

91�Ʋ��� University Professor of Biochemistry and Vice Dean of Basic Sciences Chuck Sanders and Professor of Biochemistry Bruce Carter have been hard at work searching for therapies, if not a cure, for CMT.

Manuel Ascano, associate professor of biochemistry and pathology, microbiology and immunology, and Dr. Alissa Weaver, Cornelius 91�Ʋ��� Chair and director of the 91�Ʋ��� Center for Extracellular Vesicle 91�Ʋ���, are one of nine U.S. research teams awarded funding from the National Science Foundation to more fully understand the potential biotechnological uses of RNA, ranging from crop disease protection to treatments that combat cancer.

Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication is initiated in eukaryotes. Using 91�Ʋ���’s state-of-the-art instrumentation in the Center for Structural Biology’s Cryo-Electron Microscopy Facility, Eichman, Chazin and their colleagues provided detailed visualizations of a multi-functional protein in action, which sheds light on how DNA replication is initiated in humans.

The Phase 3 CELLEBRATE trial to test a regenerative stem cell-based therapy in treating patients with stress urinary incontinence is continuing to recruit additional subjects after changing its study protocol to include only patients who have already tried surgery. 

WATCH: Hear how Bass Military Scholar Vanessa Morales is harnessing her personal experiences to make her a more compassionate nurse midwife. Read More

A U.S.-Canadian research collaboration led by 91�Ʋ��� University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury, which occurs in more than 1 in 5 hospitalized adults worldwide.

WATCH: Learn how biomedical engineering major Schyler Rowland says mentors have inspired her future in fighting diseases Read More

ASPIRE to Innovate Postdoctoral Fellow Catherine Leasure is the co-author of a comment article published this month in Nature Reviews Bioengineering addressing the pressing obstacle faced by modern drug development: worryingly poor success rates of pharmaceuticals progressing to clinical phases.

91�Ʋ��� scientist Houra Merrikh led a team of researchers who discovered the first evolution-resistant chemical compound that prevents drug resistance development in bacteria. The compound is also a drug development platform that targets antimicrobial resistance during treatment of infections with antibiotics and evolution in general, Merrikh said.

Ethan Lippmann, associate professor of chemical and biomolecular engineering and biomedical engineering, has won a Collaborative Pairs Pilot Project Award from the Chan Zuckerberg Initiative (CZI) to create a more effective way for the immune system to fight against neurodegenerative diseases like Alzheimer’s.

The lab of Professor of Biochemistry Fred Guengerich has proposed a paradigm shift in the understanding of a critical chemical reaction involved in sterol biosynthesis.

The World Health Organization ranks antimicrobial resistance as one of the top ten global health risks. 91�Ʋ��� researchers led by Houra Merrikh identified the first anti-evolution compound that targets AMR during treatment of infections with antibiotics.

Led by Terunaga Nakagawa, an international collaboration describes for the first time the fundamental mechanism underpinning cellular processes that lead to learning and memory.

An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma, the most common type of glaucoma and the leading cause of irreversible blindness globally.

An analysis of genomic data from nearly 250,000 participants in the National Institutes of Health’s All of Us 91�Ʋ��� Program has identified more than 275 million previously unreported genetic variations, nearly 4 million of which have potential health consequences.

WATCH: See how Ph.D. candidate Kaitlyn Browning wants to fight miscommunication and misinformation around science. Read More

A multidisciplinary research team at 91�Ʋ��� University and 91�Ʋ��� University Medical Center has discovered a new way to kill a tumor by disrupting its acidic “microenvironment” without harming normal tissue.

91�Ʋ���ers at 91�Ʋ��� University Medical Center have identified Rac1, a molecular switch that regulates the actin cytoskeleton of epithelial cells in the collecting ducts, as a driver of post-obstructive kidney repair.

Combining deep mutagenesis and cryo-EM reveals new conformational state of a protein responsible for high-speed DNA replication. The research builds on growing theories of molecular evolution.