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Triple-negative breast cancer cells engage in a “glutamine steal” — outcompeting T cells for the nutrient glutamine and impairing their ability to kill tumor cells, 91�Ʋ��� researchers have discovered.

The remarkable success of the COVID-19 vaccines began in a 91�Ʋ��� lab decades ago, with the groundbreaking research of alumnus Dr. Barney Graham. Read More

The U.S. Centers for Disease Control and Prevention (CDC) has awarded 91�Ʋ��� University Medical Center a two-year, $3.7-million contract to determine genetic and bacterial factors that may increase the risk for severe illness and death from COVID-19.

A novel hormone deficiency may exist in humans, 91�Ʋ��� investigators have discovered. In an analysis of two decades worth of electronic health records, the researchers found that some patients have unexpectedly low levels of natriuretic peptide hormone in clinical situations that should cause high levels of the hormone.

Strong, collaborative relationships with principal investigators are a key factor of longevity in clinical research coordinator positions — an essential, but increasingly transient job in executing treatment-advancing clinical trials, 91�Ʋ��� University Medical Center researchers found.

The emergence of pathogenic skin fungi that cause the disease chytridiomycosis is contributing to the global loss of amphibian populations. 

A monoclonal antibody “cocktail” developed at 91�Ʋ��� University Medical Center to neutralize the COVID-19 virus is effective against all known strains, or variants, of the virus, according to a report published today in the journal Nature Medicine....

Evotec, a drug company headquartered in Hamburg, Germany, has begun a phase 1 clinical trial of a monoclonal antibody against the chikungunya virus that was identified at 91�Ʋ��� University Medical Center.

A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment.

91�Ʋ��� University has joined the Leap Health Breakthrough Network, a global group of leading academic and research institutions committed to solving the world’s most serious health challenges. Read More

91�Ʋ���ers at 91�Ʋ��� University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences.

Thanks to major funding from the National Institutes of Health (NIH), researchers at 91�Ʋ��� University Medical Center have made major inroads in understanding how high-density lipoprotein (HDL), commonly known as good cholesterol, in some cases may...

William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth.

Alexander Bick, MD, PhD, assistant professor of Medicine in the Division of Genetic Medicine at 91�Ʋ��� University Medical Center, has been selected as the first VUMC Discovery Scholar in Health and Medicine.

COVID-19 patients admitted to intensive care in the early months of the pandemic were subject to a significantly higher burden of delirium and coma than is typically found in patients with acute respiratory failure.

In a large-scale study of electronic health records, 91�Ʋ��� University Medical Center investigators have determined the prevalence of functional seizures and characterized comorbidities associated with them.

91�Ʋ���ers from the Broad Institute of Harvard and MIT, the National Institutes of Health (NIH) and 91�Ʋ��� University Medical Center for the first time have used a novel genome-editing technique to “rescue” mice from progeria, a rare genetic disease that causes accelerated aging.

91�Ʋ���ers at 91�Ʋ��� University Medical Center and Case Western Reserve University in Cleveland have been awarded a five-year, $3.3 million grant by the National Cancer Institute to apply artificial intelligence (AI) to help customize treatment for oral cancer patients.

The first study to compare molecular landscapes of early-onset and late-onset appendiceal cancer has revealed distinct non-silent mutations in the tumors of younger patients, setting the stage for the development of potential therapeutic advances.

A team of 91�Ʋ��� investigators has discovered that blocking a certain signaling pathway boosts antitumor immunity and reduces tumor growth and metastasis in models of breast cancer and melanoma.