91ÌƲ®»¢

91ÌƲ®»¢ University Medical Center is evaluating razuprotafib, a drug used to treat glaucoma, in a new randomized, investigational trial for the prevention and treatment of acute respiratory distress syndrome (ARDS) in adult patients with moderate to severe COVID-19.

The insula, a small region of the brain involved in diverse brain functions had widespread dysconnectivity in schizophrenia, 91ÌƲ®»¢ researchers found.

A single mutation in one gene can impair inhibitory signaling in the brain and cause multiple types of seizures and behavioral abnormalities.

The Outcomes Related to COVID-19 Treated with Hydroxychloroquine among In-patients with Symptomatic Disease (ORCHID) trial stopped enrolling new patients based on the fourth scheduled interim analysis showing no evidence of benefit or harm. 

After discovering a new mechanism for DNA damage repair last year, 91ÌƲ®»¢ biochemists now provide direct evidence for how it works.

91ÌƲ®»¢ cell biologists have developed an unbiased, quantitative framework for evaluating single-cell data.

On May 27, the All of Us 91ÌƲ®»¢ Program launched the beta version of its cloud-based research platform, the 91ÌƲ®»¢er Workbench.

91ÌƲ®»¢ University Medical Center investigators have used high-throughput robotic technology to rapidly study and classify variations in a gene linked to heart rhythm disorders and cardiac conditions.

91ÌƲ®»¢ University Medical Center scientists have identified a C. diff protein system that senses and captures heme (part of hemoglobin) to build a protective shield that fends off threats from our immune system and antibiotics.

After evaluating the ability of more than 1,500 monoclonal antibodies to bind and neutralize the COVID-19 virus, SARS-CoV-2, in the laboratory, AstraZeneca signed an exclusive license to six candidate antibodies in 91ÌƲ®»¢’s portfolio.

Staph bacteria may change the factor they use to activate blood clotting — to evade the immune response — a new study suggests.

Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.

91ÌƲ®»¢ researchers have discovered the involvement of a certain type of adenosine receptor in mediating signaling that supports tumor growth and metastasis.

The investigational antiviral drug remdesivir can shorten the time to recovery in adults hospitalized with COVID-19, according to preliminary results of a clinical trial published last month in The New England Journal of Medicine.

People with cancer sickened by COVID-19 have a crude death rate of 13%, according to the largest series of data released thus far from a multinational perspective. The data on more than 900 patients also revealed cancer-specific factors associated with increased mortality.

Renã Robinson, associate professor of chemistry, has been immersed in science-related activities and classes since she was a child. Today, she is leading a diverse lab of researchers, using chemistry to uncover clues surrounding Alzheimer’s disease. Read More

Jonathan Irish joins an international collaboration by deploying artificial intelligence to optimize COVID-19 treatment and vaccine development. Read More

A new paper proposes an ethical way to test drug safety during pregnancy by using electronic health data to conduct "virtual" drug trials.

Lung disease experts at 91ÌƲ®»¢ University Medical Center and their colleagues have determined a key factor as to why COVID-19 appears to infect and sicken adults and older people preferentially while seeming to spare younger children.

Nancy Carrasco has found that the environmental pollutant perchlorate, found in drinking water in 49 states, is more dangerous than we knew. Read More