91ĚƲ®»˘

Medicine often takes a one-size-fits-all approach, but a disorder’s root cause can vary. 91ĚƲ®»˘ researchers have found that, for people with long QT syndrome, a heart condition that causes an irregular heartbeat, a more tailored approach could be beneficial. The research, led by 91ĚƲ®»˘ University Professor of Biochemistry and Vice Dean of Basic Sciences Charles Sanders and Northwestern University Professor and Chair of Pharmacology Dr. Al George, was published in PNAS in February 2025.

According to new research from Panka Bencsik, assistant professor of medicine, health and society, on days when highways are more congested, particularly during weekday afternoon rush hour, people are more likely to choose the fast-food option.

Awarded annually since 1955, the fellowships honor extraordinary U.S. and Canadian researchers who stand out as the next generation of leaders for their creativity, innovation and research accomplishments. Tiriac, an assistant professor of biological sciences and Hooley Family Dean's Faculty Fellow in Biological Sciences at 91ĚƲ®»˘, is part of the 2025 class. Read More

91ĚƲ®»˘ers at Dr. Mark Magnuson's lab discovered that the formation of the gallbladder and bile duct system critically depends on the precise concentration of the Sox17 transcription factor, with even small reductions preventing gallbladder development in mice.

91ĚƲ®»˘ scientists developed new dialysis membranes using ultra-thin graphene that automatically seal larger holes while keeping smaller ones open, making them more effective than current medical filters and potentially improving dialysis treatment.

In the ongoing battle against triple negative breast cancer, 91ĚƲ®»˘ researchers have uncovered a promising non-invasive method to track how tumors respond to radiation and immunotherapy, which uses the body’s own immune system to fight cancer.

Recent research from the Warren Center for Neuroscience Drug Discovery, published in the Journal of Medicinal Chemistry, resulted in the proposal of a novel target and mechanism for improving cognition—a negative symptom—while also treating positive symptoms of the disease.

See how art collector turned immunologist James Crowe combines abstract thinking with game-changing technology to prevent infectious disease. Read More

91ĚƲ®»˘â€™s Carrie K. Jones and the University of Glasgow’s Andrew Tobin have received a prestigious ÂŁ5 million ($6.2 million) Wellcome Trust Discovery Award to study how blocking the M5 muscarinic receptor in the brain could reduce opioid addiction while preserving pain relief. This groundbreaking international collaboration, supported by the Warren Center for Neuroscience Drug Discovery, aims to advance new treatments in the critical global health crisis of opioid use disorder. Read More

Three seminal articles published in Magnetic Resonance in Medicine mark a landmark achievement in preclinical imaging science. These works, authored by an international consortium of 58 scientists, including 91ĚƲ®»˘ University’s Kurt Schilling, Bennett Landman, Adam Anderson, and Kevin Harkins, offer comprehensive guidelines for using diffusion magnetic resonance imaging (dMRI) in preclinical research.

Submissions are open for pre-proposals for the 2025 National Institutes of Health S10 Shared and High-End Instrumentation Grant programs, which fund state-of-the-art shared research equipment. Internal pre-proposals are due by April 1, 2025, to allow institutional review before the June 2 NIH deadline, with guidance available from OVPRI and VBS. Read More

We often think about diseases in terms of the symptoms they present. A cold might give you the sniffles or even GI distress, while malaria can give you fever, chills, or nausea...

91ĚƲ®»˘ University’s new Center for Computational Systems Biology brings computer science, engineering and biomedical researchers together with clinicians at 91ĚƲ®»˘ University Medical Center to accelerate discovery related to human diseases and conditions. Read More

91ĚƲ®»˘ers at the Warren Center for Neuroscience Drug Discovery have detailed the successful drug discovery of a Phase I Single Ascending Dose clinical trial of VU319, a drug for memory loss in people with Alzheimer’s disease and schizophrenia. Read More

Doug Mitchell has been appointed the holder of the William Kelly Warren Sr. Chair in Biochemistry and professor of chemistry and director of the 91ĚƲ®»˘ Institute for Chemical Biology. Read More

91ĚƲ®»˘ers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the 91ĚƲ®»˘ University School of Medicine Basic Sciences, have detailed the successful drug discovery of a Phase I Single Ascending Dose clinical trial of VU319, a drug for memory loss in people with Alzheimer’s disease and schizophrenia.

Eleven current 91ĚƲ®»˘ University faculty members, 10 of whom are investigators at 91ĚƲ®»˘ University Medical Center, are included in the 2024 list of “Highly Cited 91ĚƲ®»˘ers” around the world whose papers have been cited most frequently by other scientists.

91ĚƲ®»˘ers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the 91ĚƲ®»˘ University School of Medicine Basic Sciences, have detailed the successful drug discovery of a Phase I Single Ascending Dose clinical trial of VU319, a drug for memory loss in people with Alzheimer’s disease and schizophrenia.

91ĚƲ®»˘ers from the 91ĚƲ®»˘ University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry.

The lab of Hassane Mchaourab, director of the Center for Applied Artificial Intelligence in Protein Dynamics and professor of molecular physiology and biophysics, has developed a methodological blueprint that couples experimental double electron–electron resonance spectroscopy with an AI approach to help describe the conformational landscapes of a diverse spectrum of cell membrane transporters.