91ÌƲ®»¢

91ÌƲ®»¢ researchers have defined a mechanism that limits liver cell proliferation after injury in order to preserve critical metabolic functions. Read More

New findings offer a potential strategy for preventing heritable pulmonary arterial hypertension. Read More

An inability to recognize faces may be an important mechanism underlying social inhibition and may contribute to, or maintain, social anxiety. Read More

Combining therapies for melanoma that induce cell senescence and that activate the immune response may improve outcomes for patients. Read More

Because donor organs are scarce, understanding the mortality risk associated with heart transplantation is an important consideration when evaluating patients for transplant. Read More

One small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis, 91ÌƲ®»¢ researchers have discovered. Read More

A protein that suppresses a key cancer pathway in the colon may be a potential biomarker for colitis-associated tumors, researchers at 91ÌƲ®»¢ University Medical Center reported last month in the journal Gut. Read More

91ÌƲ®»¢ investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients. Read More

91ÌƲ®»¢ researchers have developed a high-throughput assay that will aid in identifying new compounds to treat preterm labor or postpartum bleeding. Read More

Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease. Read More

91ÌƲ®»¢ investigators are exploring the shape changes in a multidrug transporter to understand the mechanisms of antibacterial resistance. Read More

The 3 million prostate cancer survivors in the United States are likely to die from something other than cancer, thanks to early detection, effective treatment and the disease’s slow progression. Read More

Tonia Rex, Ph.D., and colleagues at the 91ÌƲ®»¢ Eye Institute are working to uncover how best to treat ocular trauma, the fourth leading cause of blindness worldwide. Read More

A study by researchers at 91ÌƲ®»¢ University Medical Center is offering a glimmer of hope to alcoholics who find it hard to remain sober because their abstinence is hounded by stubborn, difficult-to-treat depression. Read More

A family of proteins with critical roles in cell division, synaptic transmission and cell migration don’t all function the way scientists thought they did, according to two new studies led by 91ÌƲ®»¢ researchers. Read More

Kevin Niswender, M.D., Ph.D., a physician-scientist at 91ÌƲ®»¢ University Medical Center whose work has helped advance understanding of diseases ranging from obesity to schizophrenia, is one of 10 recipients of the 2016 Harrington Scholar-Innovator Awards. Read More

A new study, led by investigators at 91ÌƲ®»¢ University Medical Center (VUMC), confirms that the scientific pursuit of so-called big data from hospitals and clinics needn’t conflict with patient privacy. Read More

91ÌƲ®»¢ researchers have established a link between the neurotransmitter serotonin and certain behaviors of some children with autism spectrum disorder (ASD), a link that may lead to new treatments for ASD. Read More

A microRNA — a small piece of RNA involved in regulating gene expression — functions as an oncogene to drive the development of lung cancer, 91ÌƲ®»¢ University investigators have discovered. Read More

To ease data collection for clinical research and ongoing analysis of clinical processes, teams at 91ÌƲ®»¢ University Medical Center (VUMC) are working to bridge the gap between clinical systems and research systems. Read More